报告摘要
Adventures in Chemical Biology From in vivo chemistry to real-time optical medical imaging
My talk will be a potpourri of my groups research interests, that illustrate our capabilities and interdisciplinarity. Specifically:
(i). I will describe the development of unnatural chemistries carried out inside cells, with studies that include the formation of both new C-C bonds, the in situ synthesis of drugs and the in celluo generation of nanoparticles.
(ii). I will describe some of the work in which we have deployed a variety of fluorescent technologies - including fluorescent molecules - for in vivo use. My talk will discuss the application of these technologies, including first in-human studies.
报告人简介
Mark is currently Professor of Therapeutic Innovation at Queen Mary University of London, playing a leading role in the new Precision Healthcare University Research Institute.
Mark received his doctorate from the University of Oxford in 1989, followed by post-doctoral studies at Harvard and returning to the UK as a Royal Society University Research Fellow (University of Southampton). In 1997 at the age of 33 he was made a Professor of Combinatorial Chemistry setting up the UK’s Centre for Combinatorial Chemistry.